diff --git a/cpu/cc2538/dev/gpio.c b/cpu/cc2538/dev/gpio.c
index 581e52839..eb561c757 100644
--- a/cpu/cc2538/dev/gpio.c
+++ b/cpu/cc2538/dev/gpio.c
@@ -79,69 +79,41 @@ notify(uint8_t mask, uint8_t port)
   }
 }
 /*---------------------------------------------------------------------------*/
-/** \brief Interrupt service routine for Port A */
-void
-gpio_port_a_isr()
+/** \brief Interrupt service routine for Port \a port
+ * \param port Number between 0 and 3. Port A: 0, Port B: 1, etc.
+ */
+static void
+gpio_port_isr(uint8_t port)
 {
+  uint32_t base;
+  uint8_t int_status, power_up_int_status;
+
   lpm_exit();
 
   ENERGEST_ON(ENERGEST_TYPE_IRQ);
 
-  notify(REG(GPIO_A_BASE + GPIO_MIS), GPIO_A_NUM);
+  base = GPIO_PORT_TO_BASE(port);
+  int_status = GPIO_GET_MASKED_INT_STATUS(base);
+  power_up_int_status = GPIO_GET_POWER_UP_INT_STATUS(port);
 
-  GPIO_CLEAR_INTERRUPT(GPIO_A_BASE, 0xFF);
-  GPIO_CLEAR_POWER_UP_INTERRUPT(GPIO_A_NUM, 0xFF);
+  notify(int_status | power_up_int_status, port);
+
+  GPIO_CLEAR_INTERRUPT(base, int_status);
+  GPIO_CLEAR_POWER_UP_INTERRUPT(port, power_up_int_status);
 
   ENERGEST_OFF(ENERGEST_TYPE_IRQ);
 }
 /*---------------------------------------------------------------------------*/
-/** \brief Interrupt service routine for Port B */
-void
-gpio_port_b_isr()
-{
-  lpm_exit();
-
-  ENERGEST_ON(ENERGEST_TYPE_IRQ);
-
-  notify(REG(GPIO_B_BASE + GPIO_MIS), GPIO_B_NUM);
-
-  GPIO_CLEAR_INTERRUPT(GPIO_B_BASE, 0xFF);
-  GPIO_CLEAR_POWER_UP_INTERRUPT(GPIO_B_NUM, 0xFF);
-
-  ENERGEST_OFF(ENERGEST_TYPE_IRQ);
-}
-/*---------------------------------------------------------------------------*/
-/** \brief Interrupt service routine for Port C */
-void
-gpio_port_c_isr()
-{
-  lpm_exit();
-
-  ENERGEST_ON(ENERGEST_TYPE_IRQ);
-
-  notify(REG(GPIO_C_BASE + GPIO_MIS), GPIO_C_NUM);
-
-  GPIO_CLEAR_INTERRUPT(GPIO_C_BASE, 0xFF);
-  GPIO_CLEAR_POWER_UP_INTERRUPT(GPIO_C_NUM, 0xFF);
-
-  ENERGEST_OFF(ENERGEST_TYPE_IRQ);
-}
-/*---------------------------------------------------------------------------*/
-/** \brief Interrupt service routine for Port D */
-void
-gpio_port_d_isr()
-{
-  lpm_exit();
-
-  ENERGEST_ON(ENERGEST_TYPE_IRQ);
-
-  notify(REG(GPIO_D_BASE + GPIO_MIS), GPIO_D_NUM);
-
-  GPIO_CLEAR_INTERRUPT(GPIO_D_BASE, 0xFF);
-  GPIO_CLEAR_POWER_UP_INTERRUPT(GPIO_D_NUM, 0xFF);
-
-  ENERGEST_OFF(ENERGEST_TYPE_IRQ);
+#define GPIO_PORT_ISR(lowercase_port, uppercase_port) \
+void \
+gpio_port_##lowercase_port##_isr(void) \
+{ \
+  gpio_port_isr(GPIO_##uppercase_port##_NUM); \
 }
+GPIO_PORT_ISR(a, A)
+GPIO_PORT_ISR(b, B)
+GPIO_PORT_ISR(c, C)
+GPIO_PORT_ISR(d, D)
 /*---------------------------------------------------------------------------*/
 void
 gpio_init()
diff --git a/cpu/cc2538/dev/gpio.h b/cpu/cc2538/dev/gpio.h
index 33980501b..e97ba2825 100644
--- a/cpu/cc2538/dev/gpio.h
+++ b/cpu/cc2538/dev/gpio.h
@@ -210,6 +210,31 @@ typedef void (* gpio_callback_t)(uint8_t port, uint8_t pin);
 #define GPIO_DISABLE_INTERRUPT(PORT_BASE, PIN_MASK) \
   do { REG((PORT_BASE) + GPIO_IE) &= ~(PIN_MASK); } while(0)
 
+/** \brief Get raw interrupt status of port with PORT_BASE.
+ * \param PORT_BASE GPIO Port register offset
+ * \return Bit-mask reflecting the raw interrupt status of all the port pins
+ *
+ * The bits set in the returned bit-mask reflect the status of the interrupts
+ * trigger conditions detected (raw, before interrupt masking), indicating that
+ * all the requirements are met, before they are finally allowed to trigger by
+ * the interrupt mask. The bits cleared indicate that corresponding input pins
+ * have not initiated an interrupt.
+ */
+#define GPIO_GET_RAW_INT_STATUS(PORT_BASE) \
+  REG((PORT_BASE) + GPIO_RIS)
+
+/** \brief Get masked interrupt status of port with PORT_BASE.
+ * \param PORT_BASE GPIO Port register offset
+ * \return Bit-mask reflecting the masked interrupt status of all the port pins
+ *
+ * The bits set in the returned bit-mask reflect the status of input lines
+ * triggering an interrupt. The bits cleared indicate that either no interrupt
+ * has been generated, or the interrupt is masked. This is the state of the
+ * interrupt after interrupt masking.
+ */
+#define GPIO_GET_MASKED_INT_STATUS(PORT_BASE) \
+  REG((PORT_BASE) + GPIO_MIS)
+
 /** \brief Clear interrupt triggering for pins with PIN_MASK of port with
  * PORT_BASE.
  * \param PORT_BASE GPIO Port register offset
@@ -270,6 +295,14 @@ typedef void (* gpio_callback_t)(uint8_t port, uint8_t pin);
   do { REG(GPIO_PORT_TO_BASE(PORT) + GPIO_PI_IEN) &= \
        ~((PIN_MASK) << ((PORT) << 3)); } while(0)
 
+/** \brief Get power-up interrupt status of port PORT.
+ * \param PORT GPIO Port (not port base address)
+ * \return Bit-mask reflecting the power-up interrupt status of all the port
+ * pins
+ */
+#define GPIO_GET_POWER_UP_INT_STATUS(PORT) \
+  ((REG(GPIO_PORT_TO_BASE(PORT) + GPIO_IRQ_DETECT_ACK) >> ((PORT) << 3)) & 0xFF)
+
 /** \brief Clear power-up interrupt triggering for pins with PIN_MASK of port
  * PORT.
  * \param PORT GPIO Port (not port base address)