diff --git a/cpu/cc26xx-cc13xx/dev/cc26xx-uart.c b/cpu/cc26xx-cc13xx/dev/cc26xx-uart.c
index d7753066f..140a5d203 100644
--- a/cpu/cc26xx-cc13xx/dev/cc26xx-uart.c
+++ b/cpu/cc26xx-cc13xx/dev/cc26xx-uart.c
@@ -120,7 +120,7 @@ static void
 disable_interrupts(void)
 {
   /* Acknowledge UART interrupts */
-  ti_lib_int_disable(INT_UART0);
+  ti_lib_int_disable(INT_UART0_COMB);
 
   /* Disable all UART module interrupts */
   ti_lib_uart_int_disable(UART0_BASE, CC26XX_UART_INTERRUPT_ALL);
@@ -141,7 +141,7 @@ enable_interrupts(void)
     ti_lib_uart_int_enable(UART0_BASE, CC26XX_UART_RX_INTERRUPT_TRIGGERS);
 
     /* Acknowledge UART interrupts */
-    ti_lib_int_enable(INT_UART0);
+    ti_lib_int_enable(INT_UART0_COMB);
   }
 }
 /*---------------------------------------------------------------------------*/
@@ -154,7 +154,7 @@ configure(void)
    * to avoid falling edge glitches
    */
   ti_lib_ioc_pin_type_gpio_output(BOARD_IOID_UART_TX);
-  ti_lib_gpio_pin_write(BOARD_UART_TX, 1);
+  ti_lib_gpio_set_dio(BOARD_IOID_UART_TX);
 
   /*
    * Map UART signals to the correct GPIO pins and configure them as
diff --git a/cpu/cc26xx-cc13xx/dev/gpio-interrupt.c b/cpu/cc26xx-cc13xx/dev/gpio-interrupt.c
index b080a5d3f..41ac5b5c6 100644
--- a/cpu/cc26xx-cc13xx/dev/gpio-interrupt.c
+++ b/cpu/cc26xx-cc13xx/dev/gpio-interrupt.c
@@ -55,7 +55,7 @@ gpio_interrupt_register_handler(uint8_t ioid, gpio_interrupt_handler_t f)
   uint8_t interrupts_disabled = ti_lib_int_master_disable();
 
   /* Clear interrupts on specified pins */
-  ti_lib_gpio_event_clear(1 << ioid);
+  ti_lib_gpio_clear_event_dio(ioid);
 
   handlers[ioid] = f;
 
@@ -74,7 +74,7 @@ gpio_interrupt_init()
     handlers[i] = NULL;
   }
 
-  ti_lib_int_enable(INT_EDGE_DETECT);
+  ti_lib_int_enable(INT_AON_GPIO_EDGE);
 }
 /*---------------------------------------------------------------------------*/
 void
@@ -86,13 +86,13 @@ gpio_interrupt_isr(void)
   ENERGEST_ON(ENERGEST_TYPE_IRQ);
 
   /* Read interrupt flags */
-  pin_mask = (HWREG(GPIO_BASE + GPIO_O_EVFLAGS31_0) & GPIO_PIN_MASK);
+  pin_mask = (HWREG(GPIO_BASE + GPIO_O_EVFLAGS31_0) & GPIO_DIO_ALL_MASK);
 
   /* Clear the interrupt flags */
   HWREG(GPIO_BASE + GPIO_O_EVFLAGS31_0) = pin_mask;
 
   /* Run custom ISRs */
-  for(i = 0; i < NUM_GPIO_PINS; i++) {
+  for(i = 0; i < NUM_IO_MAX; i++) {
     /* Call the handler if there is one registered for this event */
     if((pin_mask & (1 << i)) && handlers[i] != NULL) {
       handlers[i](i);
diff --git a/cpu/cc26xx-cc13xx/dev/soc-rtc.c b/cpu/cc26xx-cc13xx/dev/soc-rtc.c
index 398f14d6a..110a584c5 100644
--- a/cpu/cc26xx-cc13xx/dev/soc-rtc.c
+++ b/cpu/cc26xx-cc13xx/dev/soc-rtc.c
@@ -100,7 +100,7 @@ soc_rtc_init(void)
   ti_lib_aon_rtc_channel_enable(AON_RTC_CH1);
   ti_lib_aon_rtc_enable();
 
-  ti_lib_int_enable(INT_AON_RTC);
+  ti_lib_rom_int_enable(INT_AON_RTC_COMB);
 
   /* Re-enable interrupts */
   if(!interrupts_disabled) {
diff --git a/cpu/cc26xx-cc13xx/dev/soc-trng.c b/cpu/cc26xx-cc13xx/dev/soc-trng.c
index 5c54093e8..33a217be8 100644
--- a/cpu/cc26xx-cc13xx/dev/soc-trng.c
+++ b/cpu/cc26xx-cc13xx/dev/soc-trng.c
@@ -71,7 +71,7 @@ static void
 disable_number_ready_interrupt(void)
 {
   ti_lib_trng_int_disable(TRNG_NUMBER_READY);
-  ti_lib_rom_int_disable(INT_TRNG);
+  ti_lib_rom_int_disable(INT_TRNG_IRQ);
 }
 /*---------------------------------------------------------------------------*/
 static void
@@ -79,7 +79,7 @@ enable_number_ready_interrupt(void)
 {
   ti_lib_trng_int_clear(TRNG_NUMBER_READY);
   ti_lib_trng_int_enable(TRNG_NUMBER_READY);
-  ti_lib_rom_int_enable(INT_TRNG);
+  ti_lib_rom_int_enable(INT_TRNG_IRQ);
 }
 /*---------------------------------------------------------------------------*/
 static bool
diff --git a/cpu/cc26xx-cc13xx/lpm.c b/cpu/cc26xx-cc13xx/lpm.c
index 78aa2c764..f73c7827b 100644
--- a/cpu/cc26xx-cc13xx/lpm.c
+++ b/cpu/cc26xx-cc13xx/lpm.c
@@ -127,7 +127,7 @@ lpm_shutdown(uint32_t wakeup_pin, uint32_t io_pull, uint32_t wake_on)
 
   /* Configure the wakeup trigger */
   if(wakeup_pin != IOID_UNUSED) {
-    ti_lib_gpio_dir_mode_set((1 << wakeup_pin), GPIO_DIR_MODE_IN);
+    ti_lib_gpio_set_output_enable_dio(wakeup_pin, GPIO_OUTPUT_DISABLE);
     ti_lib_ioc_port_configure_set(wakeup_pin, IOC_PORT_GPIO, io_cfg);
   }
 
@@ -584,7 +584,7 @@ lpm_pin_set_default_state(uint32_t ioid)
   }
 
   ti_lib_ioc_port_configure_set(ioid, IOC_PORT_GPIO, IOC_STD_OUTPUT);
-  ti_lib_gpio_dir_mode_set((1 << ioid), GPIO_DIR_MODE_IN);
+  ti_lib_gpio_set_output_enable_dio(ioid, GPIO_OUTPUT_DISABLE);
 }
 /*---------------------------------------------------------------------------*/
 /**
diff --git a/cpu/cc26xx-cc13xx/rf-core/rf-core.c b/cpu/cc26xx-cc13xx/rf-core/rf-core.c
index 15fc8e3bc..fa4438415 100644
--- a/cpu/cc26xx-cc13xx/rf-core/rf-core.c
+++ b/cpu/cc26xx-cc13xx/rf-core/rf-core.c
@@ -236,10 +236,10 @@ rf_core_power_up()
   uint32_t cmd_status;
   bool interrupts_disabled = ti_lib_int_master_disable();
 
-  ti_lib_int_pend_clear(INT_RF_CPE0);
-  ti_lib_int_pend_clear(INT_RF_CPE1);
-  ti_lib_int_disable(INT_RF_CPE0);
-  ti_lib_int_disable(INT_RF_CPE1);
+  ti_lib_int_pend_clear(INT_RFC_CPE_0);
+  ti_lib_int_pend_clear(INT_RFC_CPE_1);
+  ti_lib_int_disable(INT_RFC_CPE_0);
+  ti_lib_int_disable(INT_RFC_CPE_1);
 
   /* Enable RF Core power domain */
   ti_lib_prcm_power_domain_on(PRCM_DOMAIN_RFCORE);
@@ -252,8 +252,8 @@ rf_core_power_up()
 
   HWREG(RFC_DBELL_NONBUF_BASE + RFC_DBELL_O_RFCPEIFG) = 0x0;
   HWREG(RFC_DBELL_NONBUF_BASE + RFC_DBELL_O_RFCPEIEN) = 0x0;
-  ti_lib_int_enable(INT_RF_CPE0);
-  ti_lib_int_enable(INT_RF_CPE1);
+  ti_lib_int_enable(INT_RFC_CPE_0);
+  ti_lib_int_enable(INT_RFC_CPE_1);
 
   if(!interrupts_disabled) {
     ti_lib_int_master_enable();
@@ -335,8 +335,8 @@ void
 rf_core_power_down()
 {
   bool interrupts_disabled = ti_lib_int_master_disable();
-  ti_lib_int_disable(INT_RF_CPE0);
-  ti_lib_int_disable(INT_RF_CPE1);
+  ti_lib_int_disable(INT_RFC_CPE_0);
+  ti_lib_int_disable(INT_RFC_CPE_1);
 
   if(rf_core_is_accessible()) {
     HWREG(RFC_DBELL_NONBUF_BASE + RFC_DBELL_O_RFCPEIFG) = 0x0;
@@ -358,10 +358,10 @@ rf_core_power_down()
   while(ti_lib_prcm_power_domain_status(PRCM_DOMAIN_RFCORE)
         != PRCM_DOMAIN_POWER_OFF);
 
-  ti_lib_int_pend_clear(INT_RF_CPE0);
-  ti_lib_int_pend_clear(INT_RF_CPE1);
-  ti_lib_int_enable(INT_RF_CPE0);
-  ti_lib_int_enable(INT_RF_CPE1);
+  ti_lib_int_pend_clear(INT_RFC_CPE_0);
+  ti_lib_int_pend_clear(INT_RFC_CPE_1);
+  ti_lib_int_enable(INT_RFC_CPE_0);
+  ti_lib_int_enable(INT_RFC_CPE_1);
   if(!interrupts_disabled) {
     ti_lib_int_master_enable();
   }
@@ -462,10 +462,10 @@ rf_core_setup_interrupts(bool poll_mode)
   /* Clear interrupt flags, active low clear(?) */
   HWREG(RFC_DBELL_NONBUF_BASE + RFC_DBELL_O_RFCPEIFG) = 0x0;
 
-  ti_lib_int_pend_clear(INT_RF_CPE0);
-  ti_lib_int_pend_clear(INT_RF_CPE1);
-  ti_lib_int_enable(INT_RF_CPE0);
-  ti_lib_int_enable(INT_RF_CPE1);
+  ti_lib_int_pend_clear(INT_RFC_CPE_0);
+  ti_lib_int_pend_clear(INT_RFC_CPE_1);
+  ti_lib_int_enable(INT_RFC_CPE_0);
+  ti_lib_int_enable(INT_RFC_CPE_1);
 
   if(!interrupts_disabled) {
     ti_lib_int_master_enable();